decrease
Not sure about b12, but anything that is considered a "base" such as milk, tums, or other antiacids will increase absorption of adderall. Anything acidic, such as citrus, fruit juices, ect. will decrease absorption and weaken the overall effect of the drug.
Drug Interactions.
The effect of decreased albumin concentration on drug absorption is that it may cause first-pass metabolism. This may increase gastric pH levels as well.Ê
the more ionized the drug is the less absorption
Veterinary drug absorption is the uptake of a drug after administration so that it can cause some sort of alteration in the body.
if Pka value is more for acidic drug,best side for absorption will be throughout the G.i.Tract.
The process that brings a drug from the administration site into the bloodstream is called absorption. It refers to the movement of a drug from its site of administration into the bloodstream for distribution throughout the body. Factors such as route of administration, drug formulation, and physiological properties can affect drug absorption.
If you want just one factor, body weight could be it. Heart rate can also affect absorption rates. Muscle to fat ration can affect absorption. Whether you have recently eaten or drank water can be a factor. Alcohol can also affect absorption rates. Pick one I guess.
Chronic internal use may increase potassium loss with diuretics or corticosteroids or other laxative herbs. Increases risk of toxicity with cardiac glycosides and antiarrhythmic drugs. And more . . .
There are no drug interactions between azithromycin and oxycontin.
pKa of a drug is the pH at which the drug is 50% ionized and 50% non-ionized. This can affect drug absorption as the ionized form may have different solubility and permeability properties compared to the non-ionized form. Understanding the pKa of a drug can help predict its behavior in different pH environments and optimize absorption.
Probenecid (a drug treating gout) impairs riboflavin absorption, and propantheline bromide (a drug treating peptic ulcers) reportedly both delays and increases absorption.