Secretin is a hormone that controls the secretions into the duodenum, and also separately, water homeostasis throughout the body. It is produced in the S cells of the duodenum in the crypts of Lieberkühn. Its effect is to regulate the pH of the duodenal contents via the control of gastric acid secretion and buffering with bicarbonate from the centroacinar cells of the pancreas as well as intercalated ducts. It is notable for being the first hormone to be identified. In humans, the secretin peptide is encoded by the SCTgene.
The gastrin, secretin, and cholecystokinin
cholecystokinin and secretin
SECRETIN
Secretin is a hormone, not an enzyme. It is produced by the duodenum in response to the presence of acid in the stomach, and it helps to stimulate the release of bicarbonate-rich pancreatic juices to neutralize the acid entering the small intestine.
Secretin is a hormone released by the small intestine. Like insulin, the presence of food in the stomach triggers it to release secretin which in turn triggers the pancreas and liver to release bile and pancreatic juice for food breakdown and absorption.
When highly acidic chyme enters the duodenum, the hormone secretin is released. Secretin stimulates the pancreas to release bicarbonate-rich fluids to neutralize the acidity of chyme coming from the stomach.
It inhibits the secretions of the stomach.
secretin..
Small intestine
Gastrin, secretin, and cholecystokinin are examples of hormones that play roles in the regulation of the digestive system. Gastrin stimulates gastric acid secretion, secretin stimulates pancreatic bicarbonate secretion, and cholecystokinin stimulates gallbladder contraction and pancreatic enzyme secretion.
Secretin and cholecystokinin
It stimulates the liver to secrete bile.