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ibuprofen is not a drug that lends itself well to lethal overdose. Its methods of effect are comparatively safe, across the board. And -- the overdose limit has not been calclulated as there have been so few deaths from overdose for this med, and of the few that have occurred, a myriad of variables applied to each (history of renal failure, active GI bleed, etc.). When overdoses to occur, two main areas seem to crop up. Ibuprofin is acidic, so it can cause irritation to the GI tract and exacerbate ulcers. Also, it shuts down the urinary tract, which in turn can result in renal damage if not corrected quickly. Like all serious overdoses, this should be handled by a doctor. First aid includes: * As with acids in general, do Not induce emesis. * Don't administer water unless you are certain of systemic dehydration, until you're sure the urinary tract is on line.

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17y ago

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