cancer cells it produce an enzyme (telomerase) that make cells dividing uncontrolled.
contain high level of telomerase enzyme
No, telomerase is typically not active in somatic cells.
Telomerase extends the end of DNA at the telomeres.
Volcanoes with high levels of water in their lava produce ash, those with dry lava produce no ash.
Telomerase is typically active during cell division to maintain the length of telomeres, which are protective caps on the ends of chromosomes. In most somatic cells, telomerase activity is low or absent, but in stem cells, germ cells, and cancer cells, telomerase is more active to prevent telomere shortening.
Telomerase maintains the telomeres of chromosomes in order to prevent cell death. This enzyme added sequences onto the ends of the chromosomes, thereby preventing extreme shortening and loss of genetic material. In a way, telomerase would give cells immortal life, by continuously regenerating its ends. However, telomerase are usually inactive in the human body because normal cells do not divide frequently, and therefore, the chromosomes do not shorten.
Telomerase function is to protect the chromosome ends. This protein binds to the ends of the chromosomes solving issues with DNA end replication
Zhou Songyang has written: 'Telomeres and telomerase' -- subject(s): Telomerase, Laboratory manuals, Physiology, Telomere
telomerase
Yes, telomerase activation can be advantageous in certain types of human body cells, particularly stem cells and germ cells. In these cells, telomerase helps maintain telomere length, allowing for continuous division and the potential for tissue regeneration and repair. Additionally, in some cancer therapies, telomerase inhibitors are being explored to target cancer cells, which often express telomerase to sustain their rapid proliferation. However, excessive telomerase activity can also contribute to tumorigenesis, so its regulation is critical.
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