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Telomerase is typically active during cell division to maintain the length of telomeres, which are protective caps on the ends of chromosomes. In most somatic cells, telomerase activity is low or absent, but in stem cells, germ cells, and cancer cells, telomerase is more active to prevent telomere shortening.
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Where is active telomerase found in?
Active telomerase is commonly found in stem cells, germ cells, and cancer cells. It is also present in some cells undergoing rapid proliferation, such as embryonic cells.
What does the telomerase enzyme do?
Telomerase maintains the telomeres of chromosomes in order to prevent cell death. This enzyme added sequences onto the ends of the chromosomes, thereby preventing extreme shortening and loss of genetic material. In a way, telomerase would give cells immortal life, by continuously regenerating its ends. However, telomerase are usually inactive in the human body because normal cells do not divide frequently, and therefore, the chromosomes do not shorten.
What is telomerase. In what cells is telomerase normally functioning?
Telomerase is an enzyme that adds repetitive nucleotide sequences to the ends of chromosomes, known as telomeres, thereby preventing their shortening during cell division. It is primarily active in stem cells, germ cells, and certain types of cancer cells, allowing these cells to maintain their ability to divide indefinitely. In most somatic cells, telomerase activity is low or absent, leading to gradual telomere shortening and eventual cellular aging.
The enzyme telomerase solves the problem of replication by?
Telomerase helps solve the problem of DNA replication by adding repetitive sequences to the ends of chromosomes, known as telomeres. This prevents the loss of important genetic information during each round of cell division. By preserving the length of telomeres, telomerase maintains the stability and integrity of chromosomes.
Are there any types of human body cells where telomerase activation would be advantageous or even necessary?
Yes, telomerase activation can be advantageous in certain types of human body cells, particularly stem cells and germ cells. In these cells, telomerase helps maintain telomere length, allowing for continuous division and the potential for tissue regeneration and repair. Additionally, in some cancer therapies, telomerase inhibitors are being explored to target cancer cells, which often express telomerase to sustain their rapid proliferation. However, excessive telomerase activity can also contribute to tumorigenesis, so its regulation is critical.
Is telomerase active in somatic cells?
No, telomerase is typically not active in somatic cells.
Where is active telomerase found in?
Active telomerase is commonly found in stem cells, germ cells, and cancer cells. It is also present in some cells undergoing rapid proliferation, such as embryonic cells.
What does the telomerase enzyme do?
Telomerase maintains the telomeres of chromosomes in order to prevent cell death. This enzyme added sequences onto the ends of the chromosomes, thereby preventing extreme shortening and loss of genetic material. In a way, telomerase would give cells immortal life, by continuously regenerating its ends. However, telomerase are usually inactive in the human body because normal cells do not divide frequently, and therefore, the chromosomes do not shorten.
What is telomerase. In what cells is telomerase normally functioning?
Telomerase is an enzyme that adds repetitive nucleotide sequences to the ends of chromosomes, known as telomeres, thereby preventing their shortening during cell division. It is primarily active in stem cells, germ cells, and certain types of cancer cells, allowing these cells to maintain their ability to divide indefinitely. In most somatic cells, telomerase activity is low or absent, leading to gradual telomere shortening and eventual cellular aging.
At what end of the DNA does telomerase extend?
Telomerase extends the end of DNA at the telomeres.
The enzyme telomerase solves the problem of replication by?
Telomerase helps solve the problem of DNA replication by adding repetitive sequences to the ends of chromosomes, known as telomeres. This prevents the loss of important genetic information during each round of cell division. By preserving the length of telomeres, telomerase maintains the stability and integrity of chromosomes.
What is the function of telomerase?
Telomerase function is to protect the chromosome ends. This protein binds to the ends of the chromosomes solving issues with DNA end replication
What has the author Zhou Songyang written?
Zhou Songyang has written: 'Telomeres and telomerase' -- subject(s): Telomerase, Laboratory manuals, Physiology, Telomere
Is telomerase a ribozyme?
No, it is an enzyme. Some textbooks claim it to be a ribozyme, but it is definitely an cellular enzyme. It has a reverse transcriptase part and a rna part. it uses the rna part as a primer and elongates the 3' end of a DNA strand which has been shortened during replication. It is usually not expressed in eucryotic cells but is active in proliferating eucaryotic cells such as germ cells. In tumor cells telomerase may be re-activated and thus the cell proliferates unrestrainedly.
What are both aging and cancer caused by?
telomerase
Are there any types of human body cells where telomerase activation would be advantageous or even necessary?
Yes, telomerase activation can be advantageous in certain types of human body cells, particularly stem cells and germ cells. In these cells, telomerase helps maintain telomere length, allowing for continuous division and the potential for tissue regeneration and repair. Additionally, in some cancer therapies, telomerase inhibitors are being explored to target cancer cells, which often express telomerase to sustain their rapid proliferation. However, excessive telomerase activity can also contribute to tumorigenesis, so its regulation is critical.
Do humans possess telomerase, the enzyme responsible for maintaining the length of telomeres?
Yes, humans do possess telomerase, the enzyme responsible for maintaining the length of telomeres.
