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Is telomerase a ribozyme

Updated: 4/28/2022
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13y ago

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No, it is an enzyme. Some textbooks claim it to be a ribozyme, but it is definitely an cellular enzyme. It has a reverse transcriptase part and a rna part. it uses the rna part as a primer and elongates the 3' end of a DNA strand which has been shortened during replication. It is usually not expressed in eucryotic cells but is active in proliferating eucaryotic cells such as germ cells. In tumor cells telomerase may be re-activated and thus the cell proliferates unrestrainedly.

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Q: Is telomerase a ribozyme
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