Telomerase
The two main ones are DNA-polymerase and helicase
DNA Polymerase III is responsible for adding new nucleotides to the strand being synthesised. Also involved in DNA replication are DNA Polymerase I which replaces primers with nucleotides, and DNA Ligase which joins fragments of DNA together.
DNA Helicase - responsible for separating the two stands DNA Polymerase - responsible for catalyzing the addition of bases to the new strand DNA Ligase - responsible for sealing fragments
During DNA replication, the lagging strand is replicated ~1000 (E. coli) base pairs at a time, forming numerous "Okazaki fragments".Okazaki fragments form because polymerase is only able to replicate DNA in one direction, but DNA is double stranded, with the strands running anti parallel (in opposite directions). The polymerase waits for a region of DNA to be unwound, and while the leading strand is replicated continuously, on the lagging strand the polymerase waits until a region of single stranded DNA is produced before replicating it. This discontinous replication forms the Okazaki fragments, which can then be joined together by ligase (although a different polymerase enzyme, pol I in E. coli, is needed as well to replace the RNA primers with DNA).
it ties the chunks of dna together
The two main ones are DNA-polymerase and helicase
DNA Polymerase III is responsible for adding new nucleotides to the strand being synthesised. Also involved in DNA replication are DNA Polymerase I which replaces primers with nucleotides, and DNA Ligase which joins fragments of DNA together.
DNA Polymerase III is responsible for adding new nucleotides to the strand being created. DNA Polymerase I replaces the primers with DNA nucleotides. The fragments are then joined together by ligase, and a new strand has been created.
Primase in the DNA-dependent RNA polymerase enzyme that functions in DNA replication by synthesizing the RNA primers which are then extended by DNA polymerase to yield newly synthesized DNA fragments. While being an RNA polymerase, primase is different from the RNA polymerase that functions in the transcription of DNA.
DNA Helicase - responsible for separating the two stands DNA Polymerase - responsible for catalyzing the addition of bases to the new strand DNA Ligase - responsible for sealing fragments
Polymerise dna fragments
There is no single enzyme responsible for DNA duplication. But the most important ones are:Helicase: it unwinds the DNA helixRNA polymerase: adds the RNA primerDNA polymerase: adds the complementary strand of DNALigase: attaches the DNA fragments together
The main enzymes involved in DNA replication are: Helicase: unwinds the double helix into two strands Polymerase: adds nucleotides to an existing strand Ligase: brings together the Okazaki fragments Topoisomerase: cuts and rejoins the helix RNA primase: catalyzes the synthesis of RNA primers Hope this helps!
During DNA replication, the lagging strand is replicated ~1000 (E. coli) base pairs at a time, forming numerous "Okazaki fragments".Okazaki fragments form because polymerase is only able to replicate DNA in one direction, but DNA is double stranded, with the strands running anti parallel (in opposite directions). The polymerase waits for a region of DNA to be unwound, and while the leading strand is replicated continuously, on the lagging strand the polymerase waits until a region of single stranded DNA is produced before replicating it. This discontinous replication forms the Okazaki fragments, which can then be joined together by ligase (although a different polymerase enzyme, pol I in E. coli, is needed as well to replace the RNA primers with DNA).
During DNA replication Okazaki fragments are joined together by DNA polymerase. Remember that Okazaki fragments start with an RNA primer so RNAse H is need to remove the primer follwed by DNA plymerase to add nucleotides and finally DNA ligase to seal the single strand nick.
it ties the chunks of dna together
If you are referring to the fragmented lagging strand for DNA replication, the fragments are called Okazaki fragments.