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The fastest way a substance can reach the brain is by inhalation into the lungs. This does not mean a tablet can be crushed up and breathed in! In order for th blood to absorb the substance from the lungs, the drug must be in gaseous form. While intravenous injection is technically slower, the difference is only a matter of a few seconds. Once a drug is introduced into bloodstream, it quickly makes its way through the heart, lungs, and to the brain. Regardless, whether a drug is aspirated or injected it will reach the brain in less than 5-10 seconds, far faster than any other method of ingestion.

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