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Even though Codeine is a Controlled Substance - Schedule V,

Many apothecaries and small family owned pharmacies will sell you cough syrups containing codeine.

You cannot purchase codeine without a prescription from the major pharmacy chains - i.e. CVS, Walgreen's, Rite-Aid Etc. This is not a law, it's just company policy!

The most prevalent non-prescription purchased cough syrup with codeine is Cheratussin AC made by Qualitest Pharmaceuticals, NDC 0603-1075-54.

Each 5ml contains: 10mg Codeine Phosphate, 100mg Guaifenesin, it's sugar free and also contains 4% w/v Alcohol. Under current US law there are restrictions for how much you can purchase and for a period of time, similar to Pseudo-ephedrine. You must sign a narcotic preparation log book and provide a valid government issued picture ID. According to US Law you may purchase a 4oz (118ml) bottle every 72 hours, (236mg Codeine) although most places will have you wait 1 week.

I have seen several answers to this question and they all state that you cannot purchase codeine without a prescription. THIS IS FALSE - YOU CAN PURCHASE CODEINE WITHOUT A PRESCRIPTION!

Codeine is what is known as a pro-drug. The codeine by itself has very little, if any action at all until it undergoes first-pass metabolism via your liver. An enzyme system known as the Cytochrome P450 system. Codeine is conjugated with glucuronic acid to Codeine-6-glucuronide, and 5% of the dose is O-De-methylated to Morphine. Those are responsible for the analgesia and other effects.

The popular opioid Vicodin was named as VI (roman numerals for 6) Codin (Codeine) since it is roughly 6 times stronger than codeine.

Here is a small chart of common opioids and respective strengths compared to Morphine

Codeine .05

Dextropropoxyphene(Darvon) .05 - .07

Tramadol(Ultram) .10

Pethidine(Demerol) .36

Hydrocodone(Vicodin) .6

Morphine(oral) 1

Oxycodone(Percocet) 1.5 - 2

Methadone 3-4

Morphine(IV/IM) 4

Diacetylmorphine(Heroin) 1.9 - 4.3

Hydromorphone(Dilaudid) 5

Oxymorphone(Opana) 7

Buprenorphine(Suboxone) 40

Fentanyl(Duragesic) 50 - 100

Carfentanil (Wildnil) 10,000 - 100,000 : Use for Tranquilizing Large Animals - Not for human use.

Some places that sell Cheratussin AC without a prescription in Indiana are Georges Pharmacy, (Sunman, IN - Versailles, IN - Brookville, IN), Madison Apothecary ( Madison, IN), Fagen Pharmacy (DeMotte, IN), Hooks Apothecary (Evansville, IN)

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