It is synthesized in the skin not the kidneys as some would think
Calcitriol
The active form of vitamin D is called calcitriol. It is produced in the kidneys from its precursor, calcidiol, which is formed in the liver. Calcitriol plays a crucial role in regulating calcium and phosphorus levels in the body.
The kidney secretes the hormones renin, calcitriol and erythropoietin. Renin - also known as angiotensinogenase, helps to control the body's blood pressure by regulating the balance of fluid and electrolytes in the body. Calcitriol - This is a form of Vitamin D which regulates calcium and phosphorous levels in the body. Erythropoietin - This is a glycoprotein hormone and has an important role in the production of red blood cells in the bone marrow.
will thyroid produce calcitriol when calcium level is above normal
Calcitriol
Vitamin D supplement.
calcitriol, renin, erythropoietin
Parathyroid hormone not only increases the re-absorption of calcium from the kidney but it also helps absorption in the intestines by increasing the production of vitamin D activation which also occurs in the kidney.
Most oral supplements of vitamin D are in the form of ergocalciferol. It is also available in topical (calcitriol or calcipotriene), intravenous (calcitriol), or intramuscular (ergocalciferol) formulations.
Reninerythropoietincalcitroil
The target cells of calcitriol, the active form of vitamin D, are primarily located in the intestines, kidneys, and bones. In the intestines, it promotes the absorption of calcium and phosphate. In the kidneys, it enhances the reabsorption of calcium, reducing its excretion. In bone, calcitriol regulates the activity of osteoblasts and osteoclasts, influencing bone remodeling and mineralization.
The kidneys play a crucial role in the activation of vitamin D. Vitamin D is converted into its active form, calcitriol, in the kidneys. Calcitriol is essential for maintaining calcium and phosphorus levels in the body, which are important for bone health and numerous other physiological processes.