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These are two drastically different drugs. ibuprofen largely decreases prostaglandins and works at the site and on inflammation. Ultram primarily blocks sensory information to the brain and the perception of pain is decreased. I wouldn't compare these two drugs. The answer to your question is better addressed in regard to why you are taking either of these.

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Does grapefruit juice interfere with effectiveness of tramadol?

Tramadol ALONE is NOT potentiated by grapefruit juice. Actually, quite the opposite is true. Since Tramadol is not technically an opiod and it works differently than other opiates, the way the liver processes it (and the result) is very different. Tramadol is broken down into O-desmethyltramadol by the cytochrome P450 isozyme CYP2B6, CYP2D6 and CYP3A4. O-desmethyltramadol is actually MORE POTENT than tramadol as far as Mu opiod activity, and thus, you WANT the liver to be converting Tramadol into O-desmethyltramadol. So grapefruit juice actually inhibits tramadol's effectiveness.


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Not quite, tramadol gives you a more energetic upbeat feeling, whereas hydrocodone is more relaxed. If it is pain reduction your after it depends on the amount of pain, and if your just looking to get stoned Tramadol is useless.


Is tramadol similar to percoset?

Tramadol is a mild synthetic opioid with additional properties similar to those of modern anti-depressants. Percocet is a combination of oxycodone and acetaminophen, and is a more potent analgesic than tramadol.


Which is stronger tramadol or ultracet?

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Which drug companies make tramadol?

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What drug not to take with Motrin?

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Is nucynta just like tramadol?

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