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What did researchers not do when testing thalidomide?
They tested the drug on animals, which was not a very good thing to do research wise either way, but on top of that, they didn't test it on pregnant animals.
How does the drug thalidomide work?
Thalidomide regulates the immune response by suppressing a protein, tumor necrosis factor alpha.
When and how was thalidomide baned?
Thalidomide was banned in most countries in the early 1960s after it was linked to severe birth defects when taken by pregnant women. The drug was initially introduced in the late 1950s as a sedative and treatment for morning sickness but was withdrawn from the market in 1961 following widespread reports of its harmful effects. Regulatory agencies, including the U.S. Food and Drug Administration (FDA), imposed strict regulations on drug testing and approval processes as a result of the thalidomide tragedy. Today, thalidomide is still used under strict controls for certain conditions, such as multiple myeloma, but is prohibited for use in pregnant women.
Did they trail the drug thalidomide?
Yes - there are thousands of deformed people as proof of the Thalidomide trials ! The drug Thalidomide was initially marketed as a cure for 'morning sickness' associated with early pregnancy. HOWEVER - the drug also caused deformities in the developing embryos, resulting in mental an physical abnormalities. There was a huge legal battle to get the makers of Thalidomide to accept responsibility for the flaw in their product. See the related link to Wikipedia for a detailed article on the drug - and its consequences.
What is the effect on babies by thalidomide?
Thalidomide, a drug initially prescribed for morning sickness in pregnant women during the late 1950s and early 1960s, caused severe birth defects in babies, including limb malformations, organ abnormalities, and facial deformities. Known as phocomelia, the most notable effect was the underdevelopment of arms and legs. The tragedy led to stricter regulations on drug testing and approval for pregnant women. Today, thalidomide is used under strict controls for certain conditions, but it remains a poignant reminder of the importance of drug safety.
What is the name of the drug that made pregnant women's baby's deformed?
Thalidomide
Drug of choice for type 2 lepra reactions?
Thalidomide Steroids
What drug was used in Europe and distributed in the US as a sedative for pregnant women?
Thalidomide.
What are some books about the thalidomide disaster?
Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine by Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicineby Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom
When testing a new drug researchers control for a placebo effect by using?
A placebo effect
How did they know that thalidomide was a treatment for leprosy?
Thalidomide was before used to prevent pregnancy nausea (it was also later discovered that it caused birth defects and was thus banned), but after more research and testing they discovered the positive effects it had on patients with Hansen's disease/Leprosy, and the drug was reintroduced (women have to take a pregnancy test before having it prescribed)
What is a lethal drugs?
Any drug that will kill you if taken in excess. This includes most drugs, even aspirin. A non-lethal drug would be Thalidomide. One person attempting suicide by Thalidomide woke-up a month later with a head-ache. Interestingly pregnant women taking Thalidomide will have severely deformed children - so its a complex situation.
