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Cytochalasin B is used in the micronucleus test to inhibit cytokinesis, which prevents the division of cells after mitosis, allowing for the accumulation of micronuclei in binucleated cells. This enhances the detection of genotoxic effects, as micronuclei—indicative of chromosome damage or loss—are more easily observed in cells that have not completed cell division. By using cytochalasin B, researchers can more accurately assess the clastogenic or aneugenic potential of test substances.

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5d ago

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Related Questions

What is the macronucleus and micronucleus in paramecium?

The macronucleus is larger and controls all functions except reproduction. The micronucleus is smaller and controls reproduction. Some paramecium have more than one micronucleus, but all have at least one.


What the function of micronucleus?

The macronucleus is larger and controls all functions except reproduction. The micronucleus is smaller and controls reproduction. Some paramecium have more than one micronucleus, but all have at least one.


Which structure of a paramecium is analogous to a reserve copy of all the cell's genes?

Micronucleus is a structure of a paramecium that is analogous to a reserve library


What are the names and functions of the nuclei in ciliates?

Ciliates have two nuclei: the macronucleus and the micronucleus. The macronucleus controls everyday functions like metabolism and growth, while the micronucleus is involved in sexual reproduction and genetic exchange.


Small nucleus found in most ciliates?

The small nucleus found in most ciliates is called the micronucleus. It is responsible for genetic recombination and sexual reproduction in ciliates, while the macronucleus is responsible for the day-to-day functioning of the cell.


What do the macronucleus and micronucleus?

macronucleus controls respiration protein synthesis and digestion.the exchanging of the DNA.


What are the functions of the macronucleus?

Macronucleus controls respiration and the Micronucleus stores the genitic code and functions in reproduction.


What two structures contain DNA in a paramecium?

In a paramecium, the DNA is contained within the nucleus, which serves as the main storage site for genetic information. Additionally, paramecia also have DNA within their micronucleus, which is involved in sexual reproduction and genetic exchange.


Of the two nuclei found in a ciliate which one contains a reserve copy of all the cell's genes?

MICROnucleus


What are smaller nucleus of a ciliate believed to contain backup copies of the cells gene?

The smaller nucleus of a ciliate is called the micronucleus, and it is responsible for genetic variation and sexual reproduction. It contains backup copies of the cell's genes, which are used during conjugation to exchange genetic material with another ciliate.


What is the function of micronucleus?

Micronuclei are small nuclei found in some cells, typically formed during cell division. They are important for maintaining genetic material integrity, and their presence can indicate DNA damage or chromosomal instability in a cell. Micronuclei are often used as a biomarker for genotoxicity in cells exposed to harmful substances or radiation.


Does Paramecia have more than one nucleus?

Yes they do; a macronucleus and one or more micronucleus. Both contain genetic material.