By being struck by diseases brought to the new world by Europeans. The natives had no immunity to the diseases and many died as a result. Also, Native Americans were at the bottom of the social hierarchy and treated basically as slaves.
The Columbian Exchange brought with it not only exotic fruits and animals, but also diseases that ended up killing many Natives.
the introduction of smallpox
horses
Horses
the introduction of horses to the Native Americans.
the introduction of smallpox
the introduction of smallpox
the native Americans
Horses
horses
The introduction of smallpox to the native Americans.
the introduction of horses
horses
the introduction of smallpox to the Native Americans
Native Americans (North and South) and Europeans.
Horses
Disease killed many Native Americans.
the introduction of horses to the Native Americans.