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the Mississippi River allowed access to the Southeast from the gulf coast, and was tremendously important in allowing the colonization of that part of the United States.

In addition, I would say that access to the river encouraged agriculture in the region, since without the Mississippi and its tributaries, there would have been no easy way to transport bulk commodities from the plantations to the end markets in the Northeast and in Europe.

Finally, the ease of transport also helped foster the slave trade. Transporting slaves overland would have been a much more difficult and expensive proposition than simply loading them on a boat and opening the hatch again at the destination, requiring much more manpower to keep control and opening the slavetraders to a much higher possibility of slave revolts or other mishaps.

The Mississippi river was critical in the development of southeast, and remains so even today. In later times, the Mississippi river and its tributaries allowed for the Tennessee Valley Authority to develop the system of dams that powers much of the region today, and it remains an important transport route for bulk cargo.

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