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Harvesting the roots of Chinese Knotweed will get rid of the plant. You may have to harvest them for more than one year to erradicate it totally.

Chinese Knotweed is used as an herbal medicinal in China, and it is named He Shou Wu (processed root) or Sheng He Shou Wu (fresh, unprocessed root)

9 to 30 grams of the freshl root can be boiled in water to make a tea. This tea may be used as a laxative, or to treat carbuncles, boils, or other toxic swellings.

Processing the root by cooking it with yellow rice wine and black bean juice makes to root more useful for nourishing the body. 9 to 30 gram doses of He Shou Wu are used in combination with other herbs to maintain youth.

He Shou Wu is one of the main herbs in a formula called qi bao mei ran dan... loosely translated, that means "seven-treasure pill for beautiful whiskers". The formula is said to restore gray hair to its youthful color, and prevent premature aging.

Source: Chinese Herbal Medicine Materia Medica; 3rd Edition. Bensky, Clavey, Stoger, 2004. Special:Booksources.

Roundup applied every time it shows will eventually kill it but other plants in the area may suffer.

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