NMT 2%
friability F=I-F.100/I where I =Iinitial weight of tablets , F = weight after friability. Normal limit less than 1%.
Sands friability refers to how easily sand can be broken down into smaller particles or dust when subject to pressure or friction. Sands with lower friability will be more resistant to breaking down, while sands with higher friability will be more prone to fragmentation. This property can impact the handling, transportation, and stability of sand materials in various applications.
Friability is typically measured using a friability tester, which consists of a rotating drum that tumbles a sample of tablets or granules for a specified time. After tumbling, the sample is weighed to determine the weight loss due to abrasion and breakage, which is expressed as a percentage. This percentage indicates the friability of the tablets or granules.
Friability erythema and erosion in the stomach means that the stomach is red and there is lose of the lining. It can occur from tiny sores in the stomach.
What are the advantage of the USP?
bcoz of coating. And for transport
The friability tester is typically set at 100 revolutions as this is the standard requirement in pharmacopeial guidelines for testing the friability of tablets. This number of revolutions is commonly used to simulate the handling and transportation stress that tablets may undergo during manufacturing and distribution.
Friability testing is done on all pharmaceutical tablets. The testing involves absorption rates, crushing levels and powderization, and enteric capability.
initial - final / initial x 100
what is usp of allahabad bank
USP method 905 "Uniformity of Dosage Units" describes how to calculate the weight variation for your dosage forms. If you need a copy of method simply drop me an email at waqassial@hotmail.com Regards
USP stands for unique selling proposition.