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IgM is a large antibody that cannot efficiently cross the placenta due to its size and structure. In contrast, IgG is the predominant immunoglobulin transferred from mother to child, as it can easily pass through the placental barrier. This transfer is crucial for providing the newborn with passive immunity, protecting them against infections in the early months of life. IgM remains primarily in the bloodstream, where it functions in the immune response but does not provide this type of maternal immunity to the fetus.

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3w ago

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