Osteoclasts
Bone cells that liquefy the bone matrix and release calcium into the blood are called Osteoclasts. Immature or matrix depositing bone cells are called osteoblasts.
Osteoclasts are bone cells responsible for breaking down and resorbing bone tissue, releasing calcium and minerals into the bloodstream. They play a crucial role in bone remodeling and maintenance.
Bones are dynamic in the sense that they are constantly being broken down and built back up. When blood calcium levels are low, cells called osteoclasts break down bone matrix and release the calcium into the blood. When blood calcium levels are high, cells called osteoblasts take calcium out of the blood and use it the built bone matrix.
An osteoclast.
The hormone produced by the para follicular cells of the thyroid gland is calcitonin (CT). CT can decrease the level of calcium in the blood by inhibiting the action of osteoclasts, the cells that break down bone extracellular matrix. The secretion of CT is controlled by a negative feedback system. When its blood level is high,calcitonin lowers the amount of blood calcium and phosphates by inhibiting bone resorption (breakdown of bone extracellular matrix) by osteoclasts and by accelerating uptake of calcium and phosphates into bone extracellular matrix.
When the blood calcium is low, the bones in the body release calcium to supplement it. This is a condition which is known as hypocalcemia.
Osteoclast
Another name for Calcium salts in bone is hydroxyapatite. The extracellular mix in blood called plasma is the matrix.
Parathyroid hormone (PTH) increases blood calcium levels primarily by stimulating the release of calcium from bones, promoting the reabsorption of calcium in the kidneys, and enhancing the activation of vitamin D in the kidneys, which in turn increases intestinal absorption of calcium. When calcium levels in the blood drop, the parathyroid glands release PTH, which acts on target tissues to restore calcium homeostasis.
When blood calcium levels are too low, the parathyroid glands release parathyroid hormone (PTH). PTH acts to increase calcium levels in the blood by stimulating the release of calcium from bones, increasing intestinal absorption of calcium, and promoting the reabsorption of calcium in the kidneys. This hormone plays a crucial role in maintaining calcium homeostasis in the body.
the release of parathyroid hormone (PTH) from the parathyroid gland. This hormone acts to increase calcium levels in the blood by promoting the release of calcium from bones, increasing calcium absorption in the intestines, and reducing calcium excretion in the kidneys.
Parathyroid hormone (PTH) is the major controller of blood calcium levels. It acts to increase calcium levels in the blood by stimulating the release of calcium from the bones, enhancing calcium absorption in the intestines, and reducing calcium excretion in the kidneys.