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Exocrine pancreatic insufficiency (EPI) is a condition where there has been a major loss (about 90%) of the excretory function of the pancreas. In dogs, this is most commonly thought to be caused by juvenile pancreatic atrophy.

EPI patients generally present with weight loss (despite normal/increased appetite) and possibly unusual faeces.

The pancreas plays a vital role in the breakdown of food (particularly fats and protein) - so when the pancreas is not functioning properly, such as with EPI, the animal will not be able to digest and properly absorb the nutrients it eats. This is why it losses weight.

EPI can be managed with a low lipid diet and the administration of pancreatic enzymes orally.

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