Say there last name was "Smith" you would write Mr. and Mrs. Smith.
When addressing a business envelope where the husband is Mr. and the wife is Dr., the proper way to format the names is to list the titles in alphabetical order. Therefore, you would address the envelope as "Dr. and Mr. [Last Name]." For example: "Dr. and Mr. Smith." This shows respect for both titles.
How about Mr. and Mrs.
Dr. Mary Smith and Mr. James Doe
Mr. and Mrs. James J. Doe If writing to him alone, the correct form would be James J. Doe, Esquire
Pastors George and Martha Maloney
I think it would be proper to address the two married PhDs as Drs. John & Jane Doe
Addressing a husband and wife who are both Reverends: Reverends John & Jane Doe.
When addressing an envelope to the wife of a doctor who is not a doctor herself then and he is Dr. John Doe, then address the envelope to her as Mrs. John Doe or Ms. (Mrs.) Jane Doe.
Major and Mrs . . .
Dear Mr. (name) and Mrs (name)
If the letter/invitation is primarily to the reverend but also her husband: Rev. Mary Smith and Mr. John Smith If the letter/invitation is primarily to the husband but includes the wife: Mr. John Smith and Rev. Mary Smith If it is strictly a business letter and not church related: Mr. & Mrs. John Smith
A baronet is addressed as "Sir", and his wife as "Lady". Exactly how to address the envelope is a little dicey , but "Sir John Doe and Lady Doe" would be acceptable, I would think.