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It means an uncomfortable feeling, either because of drink or drugs, or because of depression or the effect of a depressing person or place.

eg your brother's so depressing that he gives me the heebie-jeebies

^Above is the modern usage. The origin of the term was actually an anti-Semitic slur. It meant "the sickening, creeped-out feeling you get when in the presence of a Hebrew (Jew)." The "Hebrew Jitters" became "heebie-jeebies."

^^

Horsefeathers.

The phrase heebie-jeebies was invented by comic writer Billy de Beck in 1923 while writing the strip Barney Google. He also coined the phrase 'hotsy totsy' and 'horsefeathers', meaning something nonsensical. This is borne out in any online etymology dictionary.

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15y ago

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