A pre-ganglionic lesion refers to damage occurring before a nerve synapses at a ganglion, affecting the axon of a neuron that transmits signals from the central nervous system to the peripheral nervous system. This type of lesion can disrupt the transmission of nerve impulses, leading to loss of function or paralysis in the affected area. It is often associated with conditions affecting the spinal cord or nerve roots. Diagnosis and treatment typically focus on addressing the underlying cause of the lesion.
could be preganglionic
sympathetic preganglionic axon parasympathetic preganglionic axon parasympathetic postganglionic axon
ACH
Preganglionic because they are myelinated. FALSE
Sympathetic preganglionic.
The parasympathetic nervous system has long preganglionic and short postganglionic fibers
The thoracic region of the spinal cord lacks autonomic preganglionic neurons. Autonomic preganglionic neurons are found in the intermediolateral cell columns of the spinal cord at the thoracolumbar (T1-L2) and sacral (S2-S4) levels.
Proximal lesion
Yes, the neurotransmitter released by both sympathetic and parasympathetic preganglionic neurons is acetylcholine. In the autonomic nervous system, preganglionic neurons from both divisions release acetylcholine to activate nicotinic receptors on postganglionic neurons. This is a key feature that differentiates the preganglionic fibers from the postganglionic fibers, where the sympathetic fibers typically release norepinephrine and the parasympathetic fibers release acetylcholine.
yes
sympathetic
Preganglionic parasympathetic fibers. In the Parasympathetic division, the preganglionic axons leave the ventral roots of the spinal cord and collectively form the pelvic splanchnic nerves.