Nothing was used in place of gunpowder during the Civil War. Gunpowder was made and used extensively by both sides.
During the Civil War the guns used black powder for propellant. Modern guns use smokeless powder, which has a completely different chemical composition.
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Chloroform was used to as an anesthesia during the Civil War.
The guns used black powder. It produced volumes of smoke and as highly corrosive to the chambers and barrels.
Weapons were used in battle during the civil war, at many battlefields in both North and South territory. The early forms of machine guns were used for the first time in the Civil War.
pretty sure the telegraph was invented during the civil war- and if not, than it was definitely used during the war
Naval battle