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Meredith Grey (the character) was approximately 32 years of age during the pilot. It premiered at the tail-end of March, 2005. That would mean that right now, in May of 2012, Meredith Grey (the character) would be 39 or 40 years old. Her other half, Dr. Derek Shepherd was in his "late 30s" (we were not given a specific number) when the show piloted. Therefore, here in 2012 he is in his mid 40s.

The numbers above are the characters only. You can Google to find out the age of the actual actress.

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13y ago

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