its on season 4
Magic Hour with Dark Chocolate and the Rod
Family Goy
Season 5, Episode 5: "Whistle While Your Wife Works"
It's season 4 episode 21. Titled "I Take Thee Quagmire."
It is impossible to know what the writers have planned but at least for the episode 'Meg and Quagmire' he did not. Perhaps the makers of Family Guy will revisit the 2 of them but as I said, it it is impossible to know that.
The Cleveland Loretta Quagmire
Cleveland Brown's wife.They divorced and then she died.
Quagmire's Baby Season 8 Episode 6
Safety Dance
Magic Hour with Dark Chocolate and the Rod
Loretta and Cleveland break up in the Season Four episode, The Cleveland-Loretta Quagmire and she is seen again (cameo, no lines) also in Season Four at Jasper's wedding in, You May Now Kiss the...Uh...Guy Who Receives she is not seen again until Season Seven, Love, Blactually where she and Cleveland say goodbye for good. She's seen again for her last appearance in the Cleveland Show episode Gone with the Wind where she is shown breaking her neck and dying after Peter destroys the upstairs of her house causing her to slide with the bathtub with her final words being Cleveland's old catch phrase... No, No, No, No
Family Goy
"Family Goy"
If you are talking about Peter's friends they are Cleveland, Joe, and Quagmire.
The episode where Quagmire is fired for crash-landing a plane is called 'Airport '07' (UK Season 6/US Season 5)
She has an affair with Quagmire... "Giggidy Goo"
Season 5, Episode 5: "Whistle While Your Wife Works"