It Caused Unexpected Damage To The Babies Of Thousands Of Pregnant Women.
The "children of thalidomide" were significant in 1958 due to the public health crisis that emerged from the use of the drug thalidomide, which was prescribed to pregnant women as a sedative and to alleviate morning sickness. The drug caused severe birth defects, including limb malformations, leading to thousands of affected children worldwide. This tragedy raised awareness about the need for stricter drug regulations and the importance of rigorous testing for pharmaceuticals, ultimately resulting in significant changes in drug approval processes, particularly in the United States and Europe. The incident became a pivotal moment in the history of medical ethics and pharmaceutical safety.
60 Minutes - 1968 Thalidomide N-O-P-D- Blues NPR 27-38 was released on: USA: 4 June 1995
Inappropriate for who, or what? Without knowing what you mean by "inappropriate," your question can't be answered. The words "appropriate" and "inappropriate" have only situational meaning. That is, anything can be appropriate or inappropriate, depending on the situation. When the situation is left unqualified, the words "appropriate" and "inappropriate" become totally meaningless. For example, a sexy green dress would be appropriate for a cocktail party, but inappropriate for a funeral. So you cannot simply ask, "Is this dress appropriate?" You have to specify: "Is this dress appropriate for a cocktail party?" or "Is this dress appropriate for a funeral?" Or, "Is this movie inappropriate?" Inappropriate for who, or what? The question needs more information: "Is this movie inappropriate for an 8-year-old child?" or "Is this movie inappropriate to watch at my grandmother's 90th birthday party?" or "Is this movie inappropriate for a romantic night at home with my boyfriend?" In other words, nothing is simply "appropriate" or "inappropriate." Whether something is appropriate or inappropriate depends on the situation, which you have failed to provide.
Yes, that is correct- to relieve nausea and morning sickness.
This question cannot be answered, for two reasons. First, there is no universal standard for what is appropriate and inappropriate in any given situation. Since we do not know what you personally think is appropriate/inappropriate for a movie to show, we cannot answer. Furthermore, you didn't mention who or what the movie is inappropriate for. Is the Godfather 2 inappropriate for who, or for what purpose? The definitions of "appropriate" and "inappropriate" are: "suitable (or not suitable) for a particular person, purpose or occasion" (definitions from dictionary.com). Unless you specify what that particular person, purpose or occasion is, your question is meaningless. By definition, whether something is appropriate or inappropriate is dependent on what it's being used for. Anything can be appropriate or inappropriate, depending on what it's being used for. For example, a sexy green dress would be appropriate for a cocktail party, but inappropriate for a funeral. So you cannot simply ask, "Is this dress appropriate?" You have to specify: "Is this dress appropriate for a cocktail party?" or "Is this dress appropriate for a funeral?" Asking, "Is this movie inappropriate?" is the same as asking, "Is this movie suitable?" Suitable for who, or what? For example, "Is this joke inappropriate?" Inappropriate for who, or what? The question needs more information: "Is this joke inappropriate to tell a 6-year-old?" or "Is this joke inappropriate to tell at a job interview?" Or, "Is this movie inappropriate?" Inappropriate for who, or what? The question needs more information: "Is this movie inappropriate for an 8-year-old child?" or "Is this movie inappropriate to watch at my grandmother's 91st birthday party?" or "Is this movie inappropriate to watch with someone whose parents just died?"
Because it failed to test the drug for its affects on developing embryos, even though it was targeted to be given to pregnant mothers to prevent morning sickness.
The chemical formula of thalidomide is C13H10N2O4.
Thalidomide was supposed to be an effective sedative for pregnant women, but thalidomide caused birth defects and peripheral neuropathy.
They tested the drug on animals, which was not a very good thing to do research wise either way, but on top of that, they didn't test it on pregnant animals.
Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine by Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicineby Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom
Thalidomide was before used to prevent pregnancy nausea (it was also later discovered that it caused birth defects and was thus banned), but after more research and testing they discovered the positive effects it had on patients with Hansen's disease/Leprosy, and the drug was reintroduced (women have to take a pregnancy test before having it prescribed)
Thalidomide was banned in most countries in the early 1960s after it was linked to severe birth defects when taken by pregnant women. The drug was initially introduced in the late 1950s as a sedative and treatment for morning sickness but was withdrawn from the market in 1961 following widespread reports of its harmful effects. Regulatory agencies, including the U.S. Food and Drug Administration (FDA), imposed strict regulations on drug testing and approval processes as a result of the thalidomide tragedy. Today, thalidomide is still used under strict controls for certain conditions, such as multiple myeloma, but is prohibited for use in pregnant women.
Thalidomide regulates the immune response by suppressing a protein, tumor necrosis factor alpha.
Pro: living organism model Con: violates the animal's rights inefficient and ineffective, their anatomy and biological reactions are not the same (look up the thalidomide tragedy)
Dr.R.Kunz and Dr.H.Keller invented thalidomide in Germany
The cast of Happy Birthday Thalidomide - 2004 includes: Mat Fraser
The thalidomide disaster could have been prevented by conducting more thorough preclinical and clinical testing to assess its safety and efficacy, particularly its potential to cause birth defects. Stronger regulations and oversight from governing bodies could have also helped prevent the tragedy by ensuring stricter approval processes for new medications. Additionally, greater transparency in reporting and communicating potential risks associated with thalidomide use could have helped raise awareness and prevent widespread harm.