History only goes back so far; humans didn't invent writing until about 4,000 years ago. So we can't be sure who were _first_ to establish trade routes through the Mediterranean Sea.
However, the first that we know of were the Phoenicians, a collection of sailing merchants who would go anywhere and buy and sell anything. The essence of "trade" or "business" is to buy things where they are plentiful and cheap, and then take them to somewhere where they are scarce and valuable. By about 1,500 BCE, the Phoenicians had been everywhere there was a sea or river between Jerusalem and London, and possibly as far north as Moscow.
Louis Lumiere invented first talking motion picture.
The first permanent trade route was created in 1482
The first movie with sound was Fritz Lang's "Siegfried" which he created in 1925, but it was a musical, and had no voice track. The first movie with talking throughout the entire movie, was "Lights Of New York", that came out in 1928 by the Warner brothers.
the Mediterranean
The wheel
During the Hellenistic Period (roughly the fourth century BC through the first century BC) Greek culture spread throughout the Mediterranean, first by Alexander the Great's conquest, then by the Roman empire.
The triangular sail was invented beginning in the 16th century. They were first seen in the Mediterranean as single yarded lateen sails.
Various concepts of morality have existed throughout human history and prehistory.
First, Greeks fish a good deal. Second, they sail trade routes from one city to another, both Greek cities and elsewhere, all over the Mediterranean Sea and the Black Sea, and make a living buying and selling things.
While the person is not known, coinage was used by the Phoenicians. The first coins appeared in the Mediterranean Sea area about 1500 BC.
Italy, surrounded by branches of the Mediterranean Sea, had a great number of ports for shipping, making it a center of great importance to all of southern Europe.
it was a radio broadcaster invented in the 1920's. it was one of the first and was widespread throughout the south
yes there are different varieties of kale. kale is a form of cabbage and one of the oldest varieties that was first grown in Mediterranean and was popular for centuries throughout Europe.
The Vikings possessed the first great navy of the Mediterranean.
They invented it. Other religions did not travel throughout the world to proselytize. They do now, but the Catholics were the first.
Sicily, then Corsica, Sardinia in and after the First Punic War. It spread to other islands throughout the Mediterranean during the Second Punic War and its aftermath.
If you are referring to the V/Stol Harrier, it was invented throughout the 1960's and entered service in the RAF in 1969. There was a previous Hawker Harrier, a sleek biplane fighter in the RAF in the 1930's.