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No, but most macromolecules are organic molecules (with a backbone made of carbon atoms). But it is possible to synthetically create macromolecules with a backbone made of silicon atoms (i.e. the silicones), boron atoms (i.e. the boranes), and a few others. The atoms attached to the backbone or forming side branches extending away from the backbone can be any element on the Periodic Table.

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What do all macromolecules have in common in each other?

they are all formed from the same elements.


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All macromolecules contain a monomer.


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They are all organic compounds, that is they contain carbon. They all contain hydrogen and oxygen too. Proteins and nucleic acids additionally have nitrogen, and nucleic acids have phosphorus. In addition, proteins, nucleic acids and polysaccharides like starch (but not simple sugars) are macromolecules.


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All macromolecules are composed of smaller subunits called monomers. When monomers combine, they form polymers through chemical bonds such as peptide bonds in proteins, glycosidic bonds in carbohydrates, and ester bonds in lipids and nucleic acids. These polymers have a large molecular weight and play essential roles in biological processes.


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