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Also small molecules.

Basically because the cell membrane is amphipathic; a polar head and non-polar tails make up the double layered membrane with non-polar tails sticking inward and polar heads outward. This means that the non-polar middle, the lipid part, does not allow hydrophyllic substances to pass easily through the membrane while non-polar substances can pass through easily. Having to do with charge and solubility.

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12y ago

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