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Why would a cancer cell need to induce angiogenesis?
As telomeres get shorter a cell loses the ability to divide
Ends of chromosomes that get shorter each time a cell divides?
Telomeres are the ends of chromosomes that shorten with each cell division due to the replication process not reaching the very end of the DNA strand. This shortening eventually leads to cellular senescence and eventually cell death. Telomeres play a crucial role in protecting the DNA and maintaining chromosome stability.
What happens when telomeres shorten?
When telomeres shorten, the cell's ability to divide and replicate gradually diminishes. This can lead to cellular senescence or programmed cell death (apoptosis), ultimately impacting tissue regeneration and overall aging. Shortened telomeres are also associated with an increased risk of age-related diseases like cancer and cardiovascular conditions.
How are telomeres replicated?
Telomeres are replicated by an enzyme called telomerase. Telomerase adds repetitive DNA sequences to the ends of chromosomes, counteracting the shortening that occurs during DNA replication. This process helps maintain the length of telomeres and preserve cell division capacity.
Heterochromatic regions at the ends of chromosomes are?
telomeres, which are essential for maintaining the stability and integrity of the chromosome. They protect the chromosome ends from degradation and prevent them from fusing with other chromosomes. Telomeres also play a role in regulating the cell's lifespan and preventing chromosomal abnormalities.
Is obesity related to telomeres?
Yes. We all begin as 1 cell and as it divides the telomeres become shorter. Larger people have more cells than smaller people and therefore have shorter telomeres.
Does the biological clock dictate when you die?
The length of your telomeres may have a lot do with the "biological clock". Telomeres are sequences of non-coding ("junk") sequences at the end of your chromosomes. Because your DNA gets a little bit shorter every time it replicates, your telomeres get shorter and shorter as you age. Once these telomeres are gone you will have more difficulty replicating DNA. The biological clock refers to your circadian rhythm, which regulates sleep/wake cycles. It is controlled by melatonin secretions by the pineal gland. In popular usage, it may also refer to a woman's age in relation to her fertility. Another words, yes/no, depends on your life style/habbits and many other factors/heir is low, but is a factor.
Why would a cancer cell need to induce angiogenesis?
As telomeres get shorter a cell loses the ability to divide
What is the protective cap of DNA on the tip of chromosomes?
The telomere is the protective cap of DNA on the tip of chromosomes. You lose a small amount of these telomeres each time the cell divides. Eventually the telomeres be lost as you age. Short chromosomes because of lack telomeres are one reason aging occurs.
What is the link between telomeres and aging?
Telomeres shorten with each cellular replication; telomere length is inversely proportional to age. While telomere extension does tend to make cells "young again", telomere extension is problematic for a treatment for age because many kinds of cancer replicate indefinitely due in part to the fact they have overactive telomerase, a protein that extends the telomeres. Until the link between cancer and telomeres is understood, telomere extension therapy will not be feasible.
Ends of chromosomes that get shorter each time a cell divides?
Telomeres are the ends of chromosomes that shorten with each cell division due to the replication process not reaching the very end of the DNA strand. This shortening eventually leads to cellular senescence and eventually cell death. Telomeres play a crucial role in protecting the DNA and maintaining chromosome stability.
What happens when telomeres shorten?
When telomeres shorten, the cell's ability to divide and replicate gradually diminishes. This can lead to cellular senescence or programmed cell death (apoptosis), ultimately impacting tissue regeneration and overall aging. Shortened telomeres are also associated with an increased risk of age-related diseases like cancer and cardiovascular conditions.
When you clone an organism why is it the same age as its genetic parent?
It's not. If done right you have a new organism. But if your source has shortened telomeres (tags on genes), then the resultant offspring will start life with shortened telomeres. It still starts as an infant, but its life expectancy is shortened.
In a diploid cell in which 2n equals 14 how many telomeres are there in each of the follow phases of the cell cycle a. G1 b. G2 c. mitotic prophase d. mitotic telophase?
There are two telomeres for each chromosome, so you need to figure out how many chromosomes there are at each stage and multiply that by two. G1-- growth phase: 14 chromosomes = 28 telomeres G2-- growth phase after replication in S phase: 28 chromosomes= 56 telomeres Mitotic Prophase-- before cell division, nuclear membrane disappears: 28 chromosomes= 56 telomeres Mitotic telophase-- nuclei separate: 14 chromosomes = 28 telomeres
What is structure is the mitotic clock?
Telomeres
How may the degradation of telomeres result in cellular aging?
It is speculated that shortening of telomeres could be the cause of aging, or could be speeding the aging process up. It is known that telomeres preserve the life of the cell and may even extend the life of the cell. To understand how aging of the cell happens, we have to look back at the life of the chromosome. The cell divides and the telomeres continue to get shorter and shorter until it reaches such a critical length that the cell loses its ability to divide. Some cells might die or as mentioned earlier, they will lose their reproductive capability, or cellular senescence. Cellular senescence will have an overall affect on the organism, contributing to decline of tissue function that is the main trait of aging. Therefore, it is right to assume that telomere dysfunction which leads to senescence, has an effect on the aging process.
At what part will DNA strand separate?
telomeres
