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Thromboplastin, also known as tissue factor, is released from damaged tissues or activated platelets during blood vessel injury. It initiates the extrinsic pathway of the coagulation cascade by forming a complex with coagulation factor VII, triggering the cascade that ultimately leads to the formation of a blood clot.

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Thromboplastin and PF3 interact to form?

Thromboplastin and PF3 interact to form a complex that activates the enzyme thrombin. This activation cascade is a crucial step in the blood clotting process, leading to the formation of a stable fibrin clot.


What is the function of thromboplastin in homeostasis?

In the final step of blood clotting cascade, Thromboplastin activates the prothrombin to Thrombin. Then the activated thrombin helps in the conversion of Fibrionogen into Fibrin (Mesh like fibrils which forms the clot).


Prothrombin converts prothrombin to?

Prothrombin is converted to thrombin by the enzyme thromboplastin. Thrombin plays a vital role in the clotting cascade by converting fibrinogen into fibrin, which forms a mesh that helps stop bleeding.


Which is the correct order in this secuence of events Big Ban Formation of galaxies formation of sun formation of earth?

Big Bang, formation of galaxies, formation of sun, formation of earth.


What is the extrinsic pathway of coagulation initiated by?

The extrinsic pathway of coagulation is initiated by the exposure of tissue factor (TF), also known as thromboplastin, which is released from damaged tissues. When blood vessels are injured, TF interacts with circulating factor VII, activating it to factor VIIa. This activated complex then catalyzes the conversion of factor X to factor Xa, leading to the formation of thrombin and subsequently fibrin, essential for blood clotting. The extrinsic pathway is crucial for the rapid response to vascular injury.

Related Questions

Which sequence is correct for the following events fibrinogen fibrin clot retraction formation of thromboplastin and prothrombin- thrombin?

The correct sequence of events is: formation of thromboplastin, conversion of prothrombin to thrombin, conversion of fibrinogen to fibrin, and finally, clot retraction. Thromboplastin initiates the coagulation cascade, leading to thrombin production, which then converts fibrinogen into fibrin, forming the clot that subsequently retracts.


Thromboplastin and PF3 interact to form?

Thromboplastin and PF3 interact to form a complex that activates the enzyme thrombin. This activation cascade is a crucial step in the blood clotting process, leading to the formation of a stable fibrin clot.


How is thromboplastin released?

Thromboplastin, also known as tissue factor, is released from damaged tissues and activated endothelial cells in response to injury. When blood vessels are damaged, the exposure of collagen and other underlying structures triggers the release of thromboplastin into the bloodstream. This protein then interacts with factor VII to initiate the extrinsic pathway of coagulation, ultimately leading to the formation of a blood clot.


Why may there be large quantities of thromboplastin in blood after surgery?

why there may be large quantities of thromboplastin in blood after surgery.


What is the role of thromboplastin with anticoagulants?

n


What are the correct order of thrombin fibrin thromboplastin prothrombin and fibrinogen inblood clotting mechanism?

Thromboplastin -> Prothrombin -> Thrombin -> Fibrinogen -> Fibrin


What is the function of thromboplastin?

Thromboplastin, also known as tissue factor, plays a crucial role in the coagulation process by initiating blood clotting. It is released from damaged tissues and interacts with factor VII in the presence of calcium ions, leading to the activation of the extrinsic pathway of coagulation. This activation ultimately results in the formation of a fibrin clot, which helps to stop bleeding and promote wound healing.


Where is thromboplastin produced?

Thromboplastin, also known as tissue factor, is produced by subendothelial cells in blood vessel walls and by blood cells called monocytes and macrophages. Upon injury to a blood vessel, thromboplastin is exposed and initiates the extrinsic pathway of blood coagulation.


Is thromboplastin released by traumatized tissue or ruptured platelets?

True


What is a Partial thromboplastin time?

A test to check your blood clotting.


What is the function of thromboplastin in homeostasis?

In the final step of blood clotting cascade, Thromboplastin activates the prothrombin to Thrombin. Then the activated thrombin helps in the conversion of Fibrionogen into Fibrin (Mesh like fibrils which forms the clot).


What tube would you draw an Activated Partial Thromboplastin Time in?

Light blue