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Beta cells in the pancreas sense extracellular glucose concentration primarily through the glucose transporter GLUT2, which facilitates glucose uptake. Once inside the cell, glucose is metabolized to produce ATP, leading to the closure of ATP-sensitive potassium channels (K_ATP channels). This depolarization triggers the opening of voltage-gated calcium channels, resulting in an influx of calcium ions and subsequent insulin secretion. This process allows beta cells to respond dynamically to changes in blood glucose levels.

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2w ago

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A concentration of sense organs and nerve cells in anterior end of the body known as?

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