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Depyrogenation of filled vials or ampoules is typically done by subjecting them to high heat, usually through dry heat sterilization or autoclaving. This process helps to remove pyrogens, which are fever-inducing substances that can be harmful if injected into the body. It is important to carefully monitor and validate the depyrogenation process to ensure that it is effective in reducing pyrogen levels to an acceptable range.

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1y ago

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