Pyrogens that are destroyed by heat.
Depyrogenation of filled vials or ampoules is typically done by subjecting them to high heat, usually through dry heat sterilization or autoclaving. This process helps to remove pyrogens, which are fever-inducing substances that can be harmful if injected into the body. It is important to carefully monitor and validate the depyrogenation process to ensure that it is effective in reducing pyrogen levels to an acceptable range.
Heat labile substances are destroyed or corrupted by heat, for example many proteins lose their structure (unfold) at temperatures considerably lower than boiling point. Heat stable substances maintain form and function at higher temperatures. Heat stable/labile properties are often used in biochemistry to distinguish organic molecules such as enzymes, cell proteins and toxins.
The best method to sterilize heat-labile solutions is by using a membrane filtration technique. This method involves passing the solution through a filter with pore sizes small enough to trap bacteria and other microorganisms, while allowing the solution to pass through intact. It is a gentle method that preserves the integrity of heat-labile substances.
Fluid, movable - not fixed
Labile mood refers to rapid and unpredictable changes in one's emotional state. Individuals with labile mood may experience sudden shifts in their mood and emotions without a specific trigger. This can make it challenging for them to regulate their feelings and reactions effectively.
Labile cells are cells that multiply constantly throughout an organisms life. Different types of labile cells are skin cells, gastrointestinal tract cells, and blood cells in bone marrow.
labile
Labile components are organic materials in the soil that decompose quickly, such as fresh plant residues. Refractory components are organic materials that decompose slowly, like lignin and humus. The distinction between labile and refractory components is important for understanding nutrient cycling in ecosystems.
1. it has no moving parts , hence heat is not produced during milling. therefore,heat-labile substances can be milled. example:- sulphonamides,vitamins,and antibiotics. 2. it is rapid and an efficint method for reducing powders to 30mm or less.
Labile cells are found in tissues that require constant regeneration, such as epithelial cells in skin, gastrointestinal tract, and bone marrow. These cells have a high turnover rate and are constantly dividing to replace old or damaged cells.
Inert ligands are stable ligands that do not easily dissociate from the metal center, while labile ligands are more reactive and can readily dissociate from the metal center. Inert ligands typically form stable and kinetically inert complexes, while labile ligands can undergo substitution reactions more easily.
There are several different definitions for the word labile. The most commonly used is to have change, be open to change or to have the ability to adapt. It can also mean unstable, moderately solid or pliable.