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Use a method called titration, where a known concentration of either a strong acid (to measure a weak base) or a strong base (to measure a weak acid) is slowly added to a solution of the unknown compound. By measuring the pH of the solution as you do the titration, and by measuring the volume of the known solution that you added to the unknown, you can determine the pKa of the unknown compound.

For complete instructions on how a titration is performed, see the Web Links to the left of this answer.

how can i determine pka value if pH is given?

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How can one determine the pKa from a titration curve?

To determine the pKa from a titration curve, identify the point on the curve where the pH is equal to the pKa value. This point represents the halfway point of the buffering region, where the concentration of the acid and its conjugate base are equal.


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The pKa value of a compound can be determined by measuring the pH at which the compound is half ionized and half unionized. This can be done through titration experiments or using specialized equipment like a pH meter. The pKa value indicates the strength of the compound as an acid or a base.


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The pKa value of H2O is approximately 15.7.


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What is the significance of pKa in determining the acidity or basicity of indicators?

The pKa value of an indicator helps determine its acidity or basicity. A lower pKa indicates stronger acidity, while a higher pKa indicates stronger basicity. This information is important in selecting the right indicator for a specific pH range in a titration.