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A nerve fiber becomes polarized when the resting potential of the membrane changes. It starts out with an unequal distribution of charges- the outside is more positive and the inside is less positive. (Sodium (Na+) is in a higher concentration on the outside of the membrane and Potassium (K+) is in a lower concentration on the inside of the membrane.) A stimulus changes the gradient- when more Na+ flows in, the resting potential changes and polarization occurs, allowing for an action potential to be propagated down the axon.

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