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I don't know if you mean the chemical processing of spent nuclear fuel, if so the Wikipedia article on PUREX will give you more information. This is an extract:

PUREX is an acronym standing for Plutonium - URanium EXtraction. The spent nuclear fuel to which this process is applied consists primarily of certain very high atomic-weight (actinoid or "actinide") elements (e.g., uranium) along with smaller amounts of material composed of lighter atoms, notably the so-called fission products. In addition to the materials intentionally placed into it (which include elements other than strictly fuel elements), the reactor environment is a veritable "alchemist's stew", inevitably "breeding" smaller amounts of many other elements and isotopes of those elements through processes like nuclear transmutation and decay. The actinoid elements in this case consist primarily of the largely unconsumed remains of the original fuel (typically U-238 and other isotopes of uranium). In addition there are smaller quantities of other actinoids, created when one isotope is transmuted into another by a reaction involving neutron capture. Plutonium-239 is the leading example. Another term sometimes seen in relation to this secondary material (and other material produced similarly) is activation products. In response to the PUREX process' ability to extract nuclear weapons materials from the spent fuel, trade in the relevant chemicals is monitored. In brief, the PUREX process is a liquid-liquid extraction ion-exchange method used to reprocess spent nuclear fuel, in order to extract primarily uranium and plutonium, independent of each other, from the other constituents.

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