How is gastric acid produced?

Answer 1

Gastrin is a hormone released by "g" cells in the stomach. This hormone stimulates gastric secretions, including hydrochloric acid (HCL). The release of gastrin is initiated by:

distention of the stomach

impulses from the vagus nerve as from sight or smell of food

presence of liquids or partially digested proteins in the stomach

I hope this answers the question!

Answer 2

· Regulation of Gastric Secretion: Parasympathetic innervations via the vagus nerve is the strongest stimulant of gastric H+ secretion. Vagal efferent activity activates parietal cells to secrete H+. Parasympathetic activation also releases gastrin from G cells. Gastrin enters the bloodstream and, via an endocrine mechanism, further stimulates the parietal cell to secrete H+. Control of the H+ Pump: Binding of histamine to receptors on parietal cells activates adenylyl cyclase and elevates cytosolic concentration of cAMP. This stimulates H+ secretion by activating basolateral K+ channels (K+ out) and apical Cl- channels (Cl- into lumen) and by causing more H+,K+-ATPase molecules and Cl- channels to be inserted into the apical membrane. Ach promotes the release of Ca++ from intracellular stores, which enhances H+ secretion by doing the same thing cAMP does. Gastrin enhances acid secretion by binding CCK receptors and releasing Ca++ from intracellular stores like Ach.

Answer 3

Gastric acid is produced by cells in the lining of the stomach called parietal cells. These cells contain proton pumps that actively transport hydrogen ions (protons) into the gastric lumen, creating a highly acidic environment. This acid, composed mainly of hydrochloric acid, plays a crucial role in the digestion of food and killing harmful bacteria.