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Immunoglobulins, more commonly referred to as antibodies.

- Immunoglobulins/antibodies are synthesized by plasma cells which is a specialized type of B-cell. Immature B-cells are produced in red bone marrow and then migrating to the spleen where some of them mature to a mature B-cell. A mature B-cell can differentiate into either a memory B-cell or a plasma cell.

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- In human adults, Immunoglobulins are synthesized by plasma cells (specialized type of B-cell) which in turn originates from red bone marrow in large bones (eg. femur).

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