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Insulin is synthesized in the endoplasmic reticulum (ER) as a precursor protein known as proinsulin. It is then transported to the Golgi apparatus, where it undergoes post-translational modifications, including cleavage into active insulin and C-peptide. From the Golgi, insulin is packaged into secretory vesicles that move towards the cell surface. Upon receiving the appropriate signals, these vesicles fuse with the plasma membrane, releasing insulin into the extracellular space.
What else can I help you with?
Which molecules are processed by the rough er?
The rough endoplasmic reticulum processes and modifies proteins synthesized by ribosomes attached to its surface. These proteins are then transported to other parts of the cell or secreted outside the cell.
What is the targeting pathway of insulin?
Endoplasmic Reticulum --> Golgi Apparatus --> outside the cell
What is an ER with ribosomes?
An endoplasmic reticulum (ER) with ribosomes on its surface is called rough endoplasmic reticulum (RER). The ribosomes on the RER are responsible for protein synthesis, which is then transported to different parts of the cell for various functions.
Do rough endoplasmic reticulum secrete protein?
Yes, the rough endoplasmic reticulum (ER) is involved in the synthesis and processing of proteins. It has ribosomes attached to its surface that help in protein synthesis. Proteins made in the rough ER are then modified, folded, and transported to other parts of the cell or outside the cell.
What maze of passageways that carry protein?
The maze of passageways that carry proteins within a cell is called the endoplasmic reticulum (ER). The ER is a network of membranes where proteins are synthesized, folded, and transported to their final destinations within or outside the cell. There are two types of ER: rough ER, which has ribosomes on its surface and is involved in protein synthesis, and smooth ER, which plays a role in lipid metabolism and detoxification.
What is the ER with ribosomes attached to its surface?
The endoplasmic reticulum (ER) with ribosomes attached to its surface is called rough endoplasmic reticulum (RER). Ribosomes on the RER are responsible for protein synthesis, which is then transported throughout the cell or secreted outside the cell.
What is the targeted pathway for insulin?
ER>Golgi>Outside of the cell.
What is insulin's target pathway?
cytoplasm to ER to outside the cell
What are insulin's targeting pathways?
ER --> Golgi --> Outside Cell
Which molecules are processed by the rough er?
The rough endoplasmic reticulum processes and modifies proteins synthesized by ribosomes attached to its surface. These proteins are then transported to other parts of the cell or secreted outside the cell.
Can you give me an example of a protein made on the rough ER that is transported out of the cell?
the ribosome
What is the targeting pathway of insulin?
Endoplasmic Reticulum --> Golgi Apparatus --> outside the cell
Does the rough er have ribosomes to make proteins?
Yes, the rough endoplasmic reticulum (ER) has ribosomes attached to its surface, which are responsible for protein synthesis. These ribosomes allow the rough ER to produce proteins that are eventually transported to other parts of the cell or outside of the cell.
What is an ER with ribosomes?
An endoplasmic reticulum (ER) with ribosomes on its surface is called rough endoplasmic reticulum (RER). The ribosomes on the RER are responsible for protein synthesis, which is then transported to different parts of the cell for various functions.
What is the function of rough er in a animal cell?
The rough endoplasmic reticulum (ER) is involved in protein synthesis and transport within the cell. It has ribosomes attached to its surface, which help in the synthesis of proteins that are then transported to other parts of the cell or secreted outside the cell.
Describe the path of a newly synthesized polypeptide from a ribosome to the cell surface?
After synthesis in the ribosome, the polypeptide chain is usually transported to the endoplasmic reticulum (ER) where it undergoes post-translational modifications and folding. From the ER, the polypeptide enters the Golgi apparatus for further processing before being packaged into vesicles and transported to the cell surface. Finally, the vesicle fuses with the cell membrane, releasing the polypeptide to the cell surface.
What cell structures are found on the surface of rough er but not on smooth er?
ribisome
