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How many introns are in CFTR?

The CFTR gene has 27 exons and 26 introns. Introns are non-coding sequences that are spliced out during mRNA processing, while exons are coding sequences that are retained in the final mRNA transcript.


How many Exons are present in EGFR?

The EGFR gene contains 28 exons.


When was CFTR - AM - created?

CFTR - AM - was created in 1962.


What change causes the protein CFTR fold improperly?

A mutation in the CFTR gene causes the protein CFTR to fold improperly. This mutation results in a defective CFTR protein that cannot function properly, leading to the development of cystic fibrosis.


What are the coding segments of a stretch of eukaryotic DNA?

Exons


In eukaryotes only exons are translated?

Correct. The mRNA transcibed from the DNA in the nucleus has both exons and introns; the introns are taken out and the exons are left in. The mended exons exit the nucleus and the introns stay in the nucleus. Only the exons are translated at the ribosomes. (In Eukaryotic cells only)


What role does cftr play in the body?

The CFTR gene provides instructions for making a protein called the cystic fibrosis transmembrane regulator.


Does cystic fibrosis have extra chromosomes?

No, cystic fibrosis is caused by mutations in the CFTR gene, not by the presence of extra chromosomes. Individuals with cystic fibrosis inherit two faulty copies of the CFTR gene, one from each parent, which leads to the production of a defective CFTR protein that affects the movement of salt and water in and out of cells.


Why are exons important?

Exons are important because they contain the genetic information needed to code for proteins. During gene expression, exons are transcribed into mRNA which is then translated into proteins. Mutations or changes in exons can alter the sequence of amino acids in a protein, leading to functional changes or diseases.


Where is the national headquarters of CFTR?

The national headquarters of the CFTR is located in the city of Boston. Boston is a city that can be found in the state of Massachusetts, which is part of the United States.


Spliced together during mrna processing?

Exons, after the introns have been cleaved.


What happens to The protein called CFTR in cystic fibrosis?

Its name is CFTR and is a membrane channel for chlorine ions. Genetic defects in CFTR brings to an increased concentration of chlorine ions that lead to a greater viscosity of mucus in several mucosae in lungs and pancreas.