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No, end plate current of excitatory post-synaptic current(EPSC) represents the sum of the currents through thousands of AChRs in the postsynaptic membrane. The end-plate potential or Excitatory post-synaptic potential(EPSP) is the local depolarisation at the post-synaptic membrane which eventually results in an action potential at the postsynaptic membrane of the neuromuscular junction. EPSP is much slower than the EPSC because of the time necessary to charge and discharge the capacitance of the muscle membrane.
Hope this helps, there is a lot more detail in the notes we were given which I'll be happy to share if you need it.
What else can I help you with?
What happens to the muscle membrane when acetylcholine binds to receptors at the motor plate?
When acetylcholine binds to receptors at the motor plate, this binding opens ligand-gated ion channels on the motor end plate, ions diffuse through the open ligand gated ion channels, and the flow of ions causes the motor end plate to reach threshold and an action potential is generated at the motor end plate.
A folded region of the sarcolemma at the neuromuscular junction?
The folded region of the sarcolemma at the neuromuscular junction is called the motor end plate. It is responsible for receiving signals from the motor neuron and initiating muscle contraction. The motor end plate is rich in acetylcholine receptors, which play a key role in neurotransmission at the neuromuscular junction.
Describe the components of the neuromuscular junction?
The neuromuscular junction consists of the motor neuron terminal, synaptic cleft, and motor end plate on the muscle fiber. When an action potential reaches the motor neuron terminal, it triggers the release of acetylcholine into the synaptic cleft. Acetylcholine then binds to receptors on the motor end plate, leading to muscle contraction.
Are end plate osteophytosis and osteoarthritis the same thing?
No, end plate osteophytosis is a type of osteophyte formation at the vertebral endplates, whereas osteoarthritis is a degenerative joint disease that affects the entire joint. End plate osteophytosis may be associated with osteoarthritis, but they are not synonymous.
What effect does depolarization have on the motor end plate once action potentials arrive at the synaptic end bulb?
Depolarization at the motor end plate upon arrival of action potentials triggers the release of neurotransmitter acetylcholine into the synaptic cleft. This acetylcholine then binds to receptors on the muscle cell membrane, initiating muscle contraction by depolarizing the muscle cell membrane and allowing the action potential to propagate along the muscle fiber.
What is the name of the neurotransmitter that produces an end plate potential?
Acetylcholine
How does the direction of an electrical circuit move on a battery device differ from the direction of an ac current?
In a DC circuit (battery), the lower potential is always on one 'end' of the circuit so the current always flows in the same direction. In a AC circuit, a wave is generated so each end cycles between high and low potential. Current always flows towards lower potential and changes direction every time the higher/ lower potential changes
How does the nervous stimulus pass to the motor end plate?
An activated neuron will send an action potential from upper motor neurons to lower motor neurons to effector organs. It is able to propagate the action potential to the motor end plate by release of neurotransmitters, chiefly acetylcholine. On the terminal bouton the action potential opens voltage gated calcium channels. There is an influx of calcium in the pre-synaptic cell and it pushes the vesicles that contain acetylcholine. These vesicles will pass through the synaptic cleft and bind to cholinergic receptors on the post synaptic neuron. Each vesicle has a miniature end plate potential of 0.5mV. In a normal action potential, it will depolarize the post synaptic motor neuron from -85mV to approximately 0-15mV. So that's approximately 180 vesicles.* The influx of neurotransmitters (primarily acetylcholine) will depolarize the motor end plate and propagate the action potential. *Threshold of an action potential is approximately -55mV so technically the minimum required to continue an action potential is around 60 vesicles.
How do you create current from Voltage?
Electric current is what flows when the voltage is applied across a resistance. Electrons flow from the negative end to the positive end. Strictly, if everything was at the same voltage no current will flow because there is no distinction, positive or negative between the ends. So people often talk more accurately of voltage difference, or potential difference.
What happens to the muscle membrane when acetylcholine binds to receptors at the motor plate?
When acetylcholine binds to receptors at the motor plate, this binding opens ligand-gated ion channels on the motor end plate, ions diffuse through the open ligand gated ion channels, and the flow of ions causes the motor end plate to reach threshold and an action potential is generated at the motor end plate.
Why the current not flowing through the wire when one end is connected to the positive terminal and the other end is let open why the positive potential does not affect the electrons in the wire?
since it is not grounded ,it does not accept the flow of current
What causes an action potential when it binds the motor end plate?
When the neurotransmitter acetylcholine binds to the motor end plate, it triggers the opening of sodium channels in the muscle cell membrane. This influx of sodium ions leads to depolarization of the cell, creating an action potential that propagates along the muscle fiber, ultimately leading to muscle contraction.
What potential motor end plate to synapse to acetylcholine synaptic cleft to special receptors on the skeletal muscle to action potential across the muscle travels down t-tubule to the what?
This is the neuromuscular junction. The action potential travels down the presynaptic motor neuron, releasing acetylcholine (ACh), which cross the synapse (neuromuscular junction), to bind to receptors on the end plate of muscle fibers, which induces depolarization, causing the muscle to contract.
Motor end plate is?
Motor end plate is a specialized area on a muscle fiber that forms a neuromuscular junction with a motor neuron. It is where the nerve impulse from the motor neuron triggers the muscle fiber to contract. The motor end plate is crucial for muscle function and movement.
A folded region of the sarcolemma at the neuromuscular junction?
The folded region of the sarcolemma at the neuromuscular junction is called the motor end plate. It is responsible for receiving signals from the motor neuron and initiating muscle contraction. The motor end plate is rich in acetylcholine receptors, which play a key role in neurotransmission at the neuromuscular junction.
Describe the components of the neuromuscular junction?
The neuromuscular junction consists of the motor neuron terminal, synaptic cleft, and motor end plate on the muscle fiber. When an action potential reaches the motor neuron terminal, it triggers the release of acetylcholine into the synaptic cleft. Acetylcholine then binds to receptors on the motor end plate, leading to muscle contraction.
Are end plate osteophytosis and osteoarthritis the same thing?
No, end plate osteophytosis is a type of osteophyte formation at the vertebral endplates, whereas osteoarthritis is a degenerative joint disease that affects the entire joint. End plate osteophytosis may be associated with osteoarthritis, but they are not synonymous.
