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RNA has the base uracil instead of thymine found in DNA. DNA is made up of thymine, adenine, cytosine and guanine. RNA is made of uracil, adenine, cytosine, guanine. DNA acts as a store of information whereas RNA acts as a messenger and is involved with protein synthesis and making copies of DNA. RNA can leave the nucleus and so is also found in the cytoplasm whereas DNA is only found in the nucleus. RNA is made from a ribose sugar whereas DNA uses a deoxyribose sugar, both of these are attached to a base. For a more detailed evaluation, have a look at http://www.diffen.com/difference/Dna_vs_Rna

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