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ACE stands for Angiotensin Converting Enzyme. Angiotensin II is the most potent vasoconstrictor in your body. In order to get from Angiotensin I to Angiotensin II, there is an enzyme required for this reaction to occur. ACE inhibitors are used to treat high blood pressure (and congestive heart failure) and they exert their effect by blocking the enzyme.

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Vasoconstriction is primarily influenced by enzymes that produce vasoconstrictive substances, such as angiotensin-converting enzyme (ACE). ACE converts angiotensin I to angiotensin II, a potent vasoconstrictor that narrows blood vessels and increases blood pressure. Other factors, such as the release of norepinephrine by the sympathetic nervous system, also contribute to vasoconstriction but are not enzymes themselves.


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