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Promoter proximal elements are regulatory DNA sequences located near the core promoter of a gene, typically within 100-200 base pairs upstream of the transcription start site. They play a crucial role in the regulation of gene expression by serving as binding sites for transcription factors and other regulatory proteins. These elements can enhance or repress transcription, depending on the specific factors that interact with them. Their proximity to the core promoter allows them to influence the recruitment of the transcriptional machinery effectively.
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What is the functional difference between enhancers and promoter proximal elements?
Enhancers are at considerable distances from the promoter and can be moved or inverted and still function. Promoter-proximal elements are close to the promoter and their position and orientation must be maintained.
In eukaryotes the interaction of enhancer and promoter elements is brought closer by?
In eukaryotes, the interaction of enhancer and promoter elements is brought closer by the bending of DNA. Proteins called transcription factors bind to enhancer elements and recruit complexes that help bend and loop the DNA, bringing the enhancer and promoter regions into close proximity for efficient gene expression.
Where does obligatory water reabsorption occur?
Obligatory water reabsorption occurs in the proximal convoluted tubule of the nephron in the kidney. This process helps to maintain the body's water balance by reabsorbing a majority of the filtered water back into the bloodstream.
The proximal end of the forearm refers to?
The olecranon is known as the proximal end of the forearm. The proximal end of the forearm refers to the olecranon.
What is proximal to the body's trunk?
The limbs (arms and legs) are proximal to the body's trunk.
What is the functional difference between enhancers and promoter proximal elements?
Enhancers are at considerable distances from the promoter and can be moved or inverted and still function. Promoter-proximal elements are close to the promoter and their position and orientation must be maintained.
Does cDNA have a promoter region?
Yes, cDNA does not have a promoter region because it is synthesized from mRNA and lacks the regulatory elements found in genomic DNA.
In eukaryotes the interaction of enhancer and promoter elements is brought closer by?
In eukaryotes, the interaction of enhancer and promoter elements is brought closer by the bending of DNA. Proteins called transcription factors bind to enhancer elements and recruit complexes that help bend and loop the DNA, bringing the enhancer and promoter regions into close proximity for efficient gene expression.
What has the author Chris Claxton written?
Chris Claxton has written: 'Examination of the CIS-elements of the rat endothelin type a promoter'
What is the proximal direction of the body?
Proximal means closer to the origin of the limb, so the knee is proximal to the ankle, and the wrist is proximal to the thumb.
Is the head distal or proximal to the shoulders?
Proximal
Is the ankle is proximal to the foot?
Proximal, anything closer to midsection in proximal (closer) than distal (distant).
What is The opposite meaning of Promoter?
The opposite of a promoter is a detractor, someone who undermines or speaks against something.
Are peyer patches in the proximal or distal intestine?
proximal ?
How do you get a dragon call promoter?
dragon promoter names
The portion of the nephron closest to the renal corpuscle is the?
Proximal tubule
Where does transcription start in a prokaryotic promoter?
Transcription in a prokaryotic promoter starts at the DNA sequence called the "promoter region."
