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Some examples of somatic gene disorders include cancer (mutations in somatic cells leading to uncontrolled cell growth), cardiovascular diseases (genetic alterations affecting heart function), and neurodegenerative diseases (such as Alzheimer's and Parkinson's, caused by mutations in somatic cells).
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What is gene therapy?
Gene therapy is a method of treatment. It is specifically used to treat patients who are suffering from diseases due to defective genes. Essentially, the treatment involves researchers replacing the defective or faulty genes with a normal functioning gene. It involves: 1) Detection of gene 2)Determination & its role 3)Isolation & cloning 4)Introducing the gene by proper way. This is either germline gene therapy (done in germ cells) or somatic gene therapy (done in somatic cells).
What are the dominate alleles?
Dominant allele disorders are single gene disorders which take effect in the heterozygous state.
Which type of disorder is most difficult to correct by gene therapy?
Multifactorial disorders, such as heart disease and diabetes, are the most difficult to correct with gene therapy. These disorders involve a combination of genetic, environmental, and lifestyle factors, making it challenging to target a single gene for treatment. Additionally, the complexity of these disorders increases the risk of unintended consequences from gene therapy.
How many gene is present in one chromosomes?
A given gene is present on exactly two chromosomes in a somatic cell.
How many alleles does a non- gamete cell have?
A non-gamete cell, or somatic cell, typically has two alleles for each gene, one inherited from each parent. This means that in diploid organisms, such as humans, somatic cells contain two sets of chromosomes, resulting in two alleles per gene. However, some organisms can have different ploidy levels, affecting the number of alleles present.
What type of gene does gene therapy try to replace in a sick person?
somatic gene
How does a somatic mutation in a gene alter the function of a cell?
A somatic mutation in a gene can alter the function of a cell by changing the instructions encoded in the gene, leading to abnormal protein production or function. This can disrupt normal cellular processes and potentially contribute to diseases like cancer.
What disorders can benefit from gene therapy?
Congenital genetic defects, epigenetic defects, and even some forms of cancer triggered by oncogene activation can all be resolved by gene therapy.In addition, acquired disorders, such as herpes or HIV infection, can also be theoretically cured by gene therapy.
What kinds of somatic cell gene mutations can frequently lead to the first stages of cancer?
Proto-oncogene is the kind of somatic cell gene mutation that can lead to first stages of cancer. Proto-oncogene can lead to cellular transformation.
What is gene therapy?
Gene therapy is a method of treatment. It is specifically used to treat patients who are suffering from diseases due to defective genes. Essentially, the treatment involves researchers replacing the defective or faulty genes with a normal functioning gene. It involves: 1) Detection of gene 2)Determination & its role 3)Isolation & cloning 4)Introducing the gene by proper way. This is either germline gene therapy (done in germ cells) or somatic gene therapy (done in somatic cells).
What are the Dominic?
Dominant allele disorders are single gene disorders which take effect in the heterozygous state.
How is gene expression controlled?
name the genetic disorders
Are alleles recessive?
Alleles can be either dominant or recessive. They can be identical or different for any given gene in a somatic cell, and can represent alternative forms of a gene.
What difference does it make if a mutation occurs in a somatic cell or in a gamete?
If the mutation occurs in a somatic cell and the cell is still able to reproduce, the mutation continues in the daughter cells in following generations. If a mutation occurs in a gamete, the original organism remains unchanged. If that gamete is used for reproduction, then the mutation will continue in the offspring.
What are the dominate alleles?
Dominant allele disorders are single gene disorders which take effect in the heterozygous state.
What are genetic disorders that involve more than one defective gene?
Some examples of genetic disorders involving more than one defective gene are cystic fibrosis, which is caused by mutations in the CFTR gene and other modifier genes; and certain types of neurofibromatosis, which result from mutations in both the NF1 and NF2 genes. These disorders demonstrate the complexity of genetic inheritance and the interactions between multiple genes.
What is the greatest risk associated with gene therapy at the present time?
Depends what kind, germ line or somatic.
