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Introduction:

Animal cells extracted from their tissue or organs are cultured in aseptic laboratory with environmental conditions same as in vivo and this technique is called as animal cell culture. Animal cells can grow as anchorage dependant or suspension culture. Cell culture techniques are used in cell and molecular Biology research and studies. Some of the important areas where cell culture plays an important role are toxicity testing, cancer research, virology, gene therapy, drug discovery and many more.

Animal Cell Culture Applications:

1.Model System:

Cell culture are used as model system to study basic cell biology and biochemistry, to study the interaction between cell and disease causing agents like bacteria, virus, to study the effect of drugs, to study the process of aging and also it is used to study triggers for ageing.

2.Cancer Research:

The basic difference between normal cell and cancer cell can be studied using animal cell culture technique, as both cells can be cultured in laboratory. Normal cells can be converted into cancer cells by using radiation, chemicals and viruses. Thus, the mechanism and cause of cancer can be studied. Cell culture can be used to determine the effective drugs for selectively destroy only cancer cells.

3.Virology:

Animal cell cultures are used to replicate the viruses instead of animals for the production of vaccine. Cell culture can also be used to detect and isolate viruses, and also to study growth and development cycle of viruses. It is also used to study the mode of infection.

4.Toxicity Testing:

Animal cell culture is used to study the effects of new drugs, cosmetics and chemicals on survival and growth of a number of types of cells.Especially liver and kidney cells. Cultured animal cells are also used to determine the maximum permissible dosage of new drugs.

5.Vaccine Production:

Cultured animal cells are used in the production of viruses and these viruses are used to produce vaccines. For example vaccines for deadly diseases like polio, rabies, chicken pox, measles and hepatitis B are produced using animal cell culture.

6.Genetically Engineered Protein:

Animal cell cultures are used to produce commercially important genetically engineered proteins such as monoclonal antibodies, insulin, hormones, and much more.

7.Replacement Tissue or Organ:

Animal cell culture can be used as replacement tissue or organs. For example artificial skin can be produced using this technique to treat patients with burns and ulcers. However research is going on artificial organ culture such as liver, kidney and pancreas. Organ culture techniques and research are being conducted on both embryonic and adult stem cell culture. These cells have the capacity to differentiate into many different types of cells and organs. It is belived that by learning to control the development and differentiation of these cells may be used to treat variety of medical conditions.

8.Genetic Counselling:

Fetal cell culture extracted from pregnant women can be used to study or examine the abnormalities of chromosomes, genes using karyotyping, and these findings can be used in early detection of fetal disorders.

9.Genetic Engineering:

Cultured animal cells can be used to introduce new genetic material like DNA or RNA into the cell. These can be used to study the expression of new genes and its effect on the health of the cell. Insect cells are used to produce commercially important proteins by infecting them with genetically altered baculoviruses.

10.Gene Therapy:

Cultured animal cells can be genetically altered and can be used in gene therapy technique. First cells are removed from the patient lacking a functional gene or missing a functional gene. These genes are replaced by functional genes and altered cells are culture and grown in laboratory condition. Then these altered cells are introduced into the patient. Another method is by using viral vector, functional gene is inserted into the genome of viral vector and then they are allowed to infect the patient, in the hope that the missing gene will be expressed with the help of the viral vector.

11.Drug Screening and Development:

Animal cell cultures are used to study the cytotoxicity of new drug. This is also used to find out the effective and safe dosage of new drugs. Now these tests are being conducted in 384 and 1536 well plates. Cell-based assay plays an important role in pharmaceutical industry.

Conclusion:

Animal cell culture technique plays an important role in research and development of drug discovery and also helps in improving the health and quality of life of patients suffering from dangerous diseases like cancer, genetic disorders.

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Why sterile conditions are needed in tissue culture?

The conditions that allow you to culture tissue are also ideal for the growth of bacteria, which given a chance will devour your tissue culture.


What is an culture tissue?

Culture tissue, often referred to as tissue culture, is a technique used to grow cells or tissues in a controlled environment outside of their natural biological context, typically in a laboratory setting. This process allows researchers to study cellular functions, genetic changes, and responses to various treatments. Tissue culture is widely used in fields such as biology, medicine, and agriculture for applications like drug testing, regenerative medicine, and plant propagation. It provides insights into cellular behavior and can lead to advancements in therapeutic techniques.


How do plant tissue differ with animal tissue?

Plant tissue contains cell walls while animal tissue contains cell membranes. Plant tissue have chloroplast organelles that are used for photosynthesis, while animal tissue lack these photosynthetic organelles.


What types of animal cells are most similar to the undifferentiated plant cells in a tissue culture?

The animal cells that are most similar to undifferentiated plant cells in a tissue culture are likely stem cells. Stem cells have the ability to divide and differentiate into various cell types, mimicking the versatility and self-renewal capacity observed in undifferentiated plant cells.


What is the difference between an animal cell and animal tissue?

You chemically can not compare them because you know that cells are building blocks and a group of cells work together to form a tissue so we can say that an animal tissue is larger than an animal cell.

Related Questions

Laboratory design for animal tissue culture laboratory?

NO


What is cross contamination in animal tissue culture?

Cross contamination means the growth of microrganism in animal cell culture.


What has the author John Anthony Sharp written?

John Anthony Sharp has written: 'An introduction to animal tissue culture' -- subject(s): Tissue culture


What has the author R Ian Freshney written?

R. Ian Freshney has written: 'Animal Cell Culture' 'Culture of Animal Cells' 'Culture of Epithelial Cells, Culture of Hematopoietic Cells and Culture of Animal Cells' 'Culture of animal cells' -- subject(s): Culture Techniques, Cultured Cells, Methods, Laboratory manuals, Tissue culture, Cell culture 'Culture of animal cells' -- subject(s): Cell culture, Culture techniques, Cultured Cells, Laboratory manuals, Tissue culture 'Cultural of Human Tumor Cells and Cultural of Epithelial Cells' 'Culture of Epithelial Cells'


Significance of tissue culture?

Tissue culture is the growth of tissues in suitable environment. They are used widely in study of maturation and growth of animal cells and plants, in cancer research, in cloning experiments etc.


What are the advantages of animal tissue culture?

controlled physiochemical and physiological environment..homogenecity of sample..economical.


Are tissue culture and plant tissue culture same?

In plant tissue culture, cells of plants are cultured. In tissue culture, cells (of plants, animals, bacteria, etc.) are cultured. Plant tissue culture is just like a subheading under tissue culture


What has the author Viswambharan Sarasan written?

Viswambharan Sarasan has written: 'Applications of tissue culture to the breeding of roses with resistance to diplocarpon rosae'


Dissertation topics in plant tissue culture?

tissue culture of mango se.


How can clone of a plant be produced?

by tissue culture method


Why sterile conditions are needed in tissue culture?

The conditions that allow you to culture tissue are also ideal for the growth of bacteria, which given a chance will devour your tissue culture.


What is an culture tissue?

Culture tissue, often referred to as tissue culture, is a technique used to grow cells or tissues in a controlled environment outside of their natural biological context, typically in a laboratory setting. This process allows researchers to study cellular functions, genetic changes, and responses to various treatments. Tissue culture is widely used in fields such as biology, medicine, and agriculture for applications like drug testing, regenerative medicine, and plant propagation. It provides insights into cellular behavior and can lead to advancements in therapeutic techniques.