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Collagen vascular diseases can lead to alterations in reticular fibers, which are primarily composed of type III collagen. These conditions can cause changes in the structure and organization of reticular fibers, resulting in weakened support for tissues and organs. As a consequence, affected tissues may lose their integrity, leading to complications such as fibrosis, impaired wound healing, or vascular issues. Additionally, these alterations may contribute to the overall pathology of the disease, affecting normal physiological functions.

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