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An elevated ACE (angiotensin-converting enzyme) level in the cerebrospinal fluid (CSF) can be seen in conditions such as sarcoidosis, a systemic inflammatory disorder that can involve the central nervous system. It is an indicator of increased immune activity in the CNS and can help in the diagnosis and monitoring of neurological involvement in sarcoidosis.

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1y ago

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Why is csf protein in newborn is high normally?

Since blood-csf barrier is not well developed in neonates protein leak from blood to csf occurs...so csf protein is high in neonates and infants...for similar reason csf protein is elevated in all meningitis due to vascular permeability...


What causes and elevated ACE?

Elevated angiotensin-converting enzyme (ACE) levels can be caused by a variety of conditions, including sarcoidosis, hyperthyroidism, and certain infections like tuberculosis. It can also be associated with some autoimmune diseases, like systemic lupus erythematosus. Additionally, certain medications, such as ACE inhibitors, can influence ACE levels. Elevated ACE may indicate increased activity in the renin-angiotensin system, often related to lung or granulomatous diseases.


How does sarcoidosis affect serum ACE kevels?

Serum ACE levels are elevated in approximately 80-90% of patients with active sarcoidosis


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